NCT07809399
Volumetric HRCT in Stable COPD Patients.
Registry fields
- Overall status
- COMPLETED
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema, Airway Obstruction
- Study type
- OBSERVATIONAL
- Intervention type
- DIAGNOSTIC_TEST
- Interventions
- Volumetric HRCT chest, Spirometry and Body Plethysmography
- Lead sponsor
- Mansoura University (OTHER)
Cached at: 2026-09-10 09:07:21
Brief summary
This study evaluates the role of volumetric high-resolution computed tomography (HRCT) of the chest in assessing patients with stable chronic obstructive pulmonary disease (COPD). COPD is a heterogeneous lung condition characterized by chronic pulmonary symptoms, structural airway/alveolar changes, and progressive airflow limitation. While spirometry provides a global assessment of lung function, it cannot localize or fully characterize specific structural abnormalities. Volumetric HRCT allows for detailed, quantitative imaging of lung parenchyma, emphysema extent, air trapping, and airway wall thickness. The primary objective of this cross-sectional observational study is to quantify emphysema, air trapping, and bronchial wall thickness in patients with stable COPD and to evaluate the relationship between these volumetric HRCT findings and clinical measures of disease severity. By identifying objective imaging parameters, this study aims to improve patient evaluation, disease staging, and clinical management.
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